Cardiovascular Disease & Medical Marijuana

Cardiovascular Disease is the number one cause of death and disability worldwide.  Chronic inflammation of the arteries (atherosclerosis), causes lesions which narrow blood vessels.  Immune and smooth muscle cells, lipids and extracellular materials amalgamate around lesions. forming plaque, which is at the core of this metabolic disorder. 

 

"When you have heart disease, you start to be tired of everything. It's like getting older. You become more white, and after that, grey. You have no feeling for anything.'

--  Gerard Depardieu,  French Actor, Filmmaker


Medical Marijuana Components Address the Root Cause of Cardiovascular Disease

According to many distinguished medical researchers their associated institutions,  compounds found in Medical Cannabis such as THC and CBD, offer great therapeutic promise in the treatment of Inflammation, the root cause of Cardiovascular Disease.

In the late 1980's, researchers discovered that the body has a receptor system that controls inflammation and tissue injury.  Fat-like molecules called endocannabinoids, fundamentally interacted with brain and body receptors - at the core of many metabolic processes, including the core inflammation mechanism of cardiovascular disease.

Further research worldwide went on to show that that find that Cannabinoids, components of Medical Cannabis, mimic the body's own endocannabinoids. If the body's own supply of Cannabinoids is in short supply, for whatever reason, supplementation with Medical Cannabis can help reestablish normal and healthy function of many systems.  New Medical Marijuana strains, high in Cannabidiol, are showing even stronger efficacy in treating inflammation than THC, and without any psychoactive effects.


How MMJ and THC Work - Control the Root Cause - Plaque Formation

THC, the active component of most Medical Marijuana strains, was discovered  to inhibit atherosclerotic plaque; natural and synthetic cannabinoid modulate the body system that controls tissue damage repair and immune response.  A receptor named CB2, was discovered to be intimately involved in the body's anti-inflammatory mechanism. 

Further study revealed that CB2 receptor malfunction plays a critical role in atherosclerosis, restenosis, stroke, myocardial infarction and heart failure. The aim in Cannabinoid therapy is to stimulate receptors CB2 to control and restore normal cellular response of; immune cells, endothelial and vascular smooth muscle cells, cardiomyocytes, monocytes/macrophages and leukocytes.


Cannabinoids, Synthetic and Natural Protect Cardiac Cells

It has been confirmed by a number of research groups that both synthetic cannabinoids and THC modulates the CB1 receptor, which was shown experimentally to regulate blood pressure and the pumping action of the heart.  Further, after a heart attack, the body's own endocannabinoids were found to protect cardiac cells.

 

" Endocannabinoids produced by the body itself exert a protective effect after a heart attack"

-- General Commentary, British Journal of Pharmacology

 

These fundamental discoveries led to deeper investigations into how Cannabinoids work.  In a breakthrough discovery, it was found that the production of nitrous oxide was activated by Cannabis and its derivatives.  It is well known that nitrous oxide has anti-anxiety, euphoric, anesthetic properties and is neuroprotective.  Which means, some of Cannabis medicinal effects are fundamentally explained.


MMJDOCTORONLINE Notes: The following studies (below) provide a further scientific basis and understand about Cannabis and how it can help treat Cardiovascular conditions and symptoms. Our Medical Marijuana Doctors provide 420 Evaluations and California Medical Marijuana Cards, here online, allowing patients to quickly and easily access the right Medical Marijuana strains and Cannabis based medications.


Further Reading - Cardiovascular Disease and Medical Cannabis

Marijuana Chemical Fights Hardened Arteries

How Medical Cannabis components offers protection of Heart Cells

Cardiovascular pharmacology of cannabinoids.

Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia

Does Cannabis Hold the Key to Treating Cardiometabolic Disease?

Cannabinoids as therapeutic agents in cardiovascular disease

Cannabinoids prevented the development of heart failure in animal study

Cardiovascular Effects of Cannabis

Targeting cannabinoid receptor CB2 in cardiovascular disorders: promises and controversies

Cannabinoid System in Neuroprotection, Raphael Mechoulam, PhD

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