High Blood Pressure & Medical Marijuana

High Blood Pressure or Hypertension, is a chronic medical condition. where artery pressure is chronically elevated above the normal range of 100–140 mmHg -  when the heart pushes blood and 60–90 mmHg - between pulses. 

The lining of blood vessels, the endothelium play a critical role in a variety of human disorders, including peripheral vascular disease, stroke, heart disease, diabetes, insulin resistance, chronic kidney failure, tumor growth, metastasis, venous thrombosis, and severe viral infectious diseases

The administration of Medical Marijuana and synthetic derivatives have also been shown to lower blood pressure without cardiotoxicity.  Components of Medical Cannabis produce an anti-inflammatory response; by reducing inflammation of the lining that impedes or restricts blood flow, the diameter of blood vessels is widened and blood pressure is reduced.

 

"A newspaper is a circulating library with high blood pressure."

--  Arthur Baer, Journalist, Funnyman


How Medical Cannabis Lowers Blood Pressure

The body's endocannabinoid system plays an important role in cardiovascular regulation and high blood pressure.  Endocannabinoids produced naturally by the body interact with the body and brain's control system that governs many bodily functions.

Cannabinoids, components of Medical Marijuana, mimic the body's endocannabinoids that are intricately involved in cardiovascular control system control.  Many studies report that Cannabinoids such as THC and CBD work by normalizing the heart's pumping action through the relaxation of overly tense muscles and tissues, allowing blood to flow more freely and normally.  These basic discoveries offer a solid scientific basis for Medical Cannabis treatment for high blood pressure and other cardiovascular disorders.  

 

"The endothelium (blood vessel lining) produces a variety of substances that play important roles in regulation of the circulation and vascular wall homeostasis (stability). The control of blood vessel wall homeostasis is achieved via production of vasorelaxants (relaxants)  and vasoconstrictors (constriction). Relaxants include and endocannabinoids)."

-- Dr. Schiffrin, Canada Research Chair and Director of the Hypertension and Vascular Research


MMJDOCTORONLINE Notes:  It is important that a licensed Medical Marijuana be consulted before taking any MMJ medication.  While Medical Cannabis works for many, Strains high in THC should not be indicated for everyone with Hypertension.  For more information, contact one of our Medical Marijuana Doctors for a Cannabis Consultation.


"One way to get high blood pressure is to go mountain climbing over molehills."

--  Earl Wilson, Old school news man


Further Reading - Research Breakthroughs

 

Cannabinoids Lower Hypertension
 

--  Blood Pressure Regulation by Endocannabinoids and their Receptors

--  Laboratory of Physiologic Studies, National Institute on Alcohol Abuse & Alcoholism, National Institutes of Health

--  Understanding Triphasic Blood Pressure Responses to Cannabinoids

"The endocannabinoid system plays a role under physiological and many pathophysiological conditions"

--  Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension

"We conclude that endoCannabinoids tonically suppress cardiac contractility in hypertension. Targeting the endocannabinoid system offers novel therapeutic strategies in the treatment of hypertension."


EndoCannabinoids - Regulation of Blood Pressure

"Cannabinoids and their endogenous and synthetic analogs exert powerful hypotensive and cardiodepressant effects by complex mechanisms involving direct and indirect effects on myocardium and vasculature."


Cannabis Therapy in Vascular Disease and Hypertension

"Cannabinoids have significant and complex effects on the vascular system that are not explained by a single mechanism or a single site of action."

--  Endocannabinoids and vascular function

--  Endocannabinoids as cardiovascular modulators

--  Towards a therapeutic use of selective CB2 cannabinoid receptor ligands for atherosclerosis.

--  Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice

 

Side Effects of Medical Marijuana

"The potential for increased use of Marijuana in the changing legal landscape suggests the need for the community to intensify research regarding the safety of Marijuana use."

--  Adverse cardiovascular, cerebrovascular, and peripheral vascular effects of marijuana inhalation: what cardiologists need to know

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