While moldy pot and chemicals account for most of the toxic effects of marijuana, there is substantial scientific that cannabis abuse, or cannabinoid hypermesis syndrome is a thing.

While moldy pot and chemicals account for most of the toxic effects of marijuana, there is substantial scientific that cannabis abuse, or cannabinoid hypermesis syndrome is a thing.

This famous author smoked strong weed 12 hours per day for many years, the result? several best sellers and a case of paranoia that upset his wife, so he quit and kept the money in the bank.  




There is much evidence that contaminants commonly found in weed cause most of the issues associated with cannabinoid hyperemesis syndrome, but there is also compelling evidence that cannabis itself could really be toxic in some cases.  


"Cannabinoid hyperemesis syndrome is generally thought to be caused by heavy, habitual use of cannabis. High THC strains are most often implicated in this disorder.  Foreign organic and chemical toxins in marijuana can also be confused with the THC and / or cannabinoid intolerance."


It would seem to be a slam dunk that taking too much THC day in and day can result in mental and physical issues, issues like paranoia, social isolation, vomiting, nausea, working basically in opposition the original intent of use.  With that said, some people that have been around marijuana for years have never heard of this condition.  Nonetheless, this disorder exists.


"I've never seen this cannabis syndrome before, never heard of it either. and I'm from the Netherlands :') "


An idea to put forward is that, no matter what the substance, too much of one thing, too long is bad for one's health.  Bodybuilders have found that cycling steroids - which dials up testosterone - and muscle growth - is far more effective in the long run by cycling.  


"When you do anything - too much - too long, the body becomes imbalanced."



How to deal with too much THC.



An interesting case cannabinoid hyperemesis syndrome


This is a very happy case in point of cannabis abuse.  A Mr. Graham Hancock, a somewhat famous flamboyant journalist-archaeologist recently admitted to his cannabis abuse.  Hancock said he started smoking pot at the age of 37.  

From a medical perspective, this means his receptors - found on the cellular membranes, which modulate many cerebral and physical functions - were virgin in the sense that they were not adapted to THC from an early age.  He went on to say, he first started smoking in the evening after work and for many years, this was nothing but pleasurable.  Life was good, marriage was good. 

Then Graham decided to experiment - to see if he could write while smoking, why not get a beautiful high while working?  He found that this worked like a charm, and he entered a most creative period of writing, with financial success as one meter.  


Smoking Pot Every Day - Is it Bad?


So what was the problem then?  

Graham goes on to explain that he started to smoke at 9 am and continued till bedtime, all the while, he kept up his long work hours and career wise, everything was on track.  Then, he and his wife went to South America, where is was inevitable that a character of this nature would partake in Ihuaska, in the Amazon with a shaman.  


Ayahuasca, a type of DMT - while non-addictive and non-toxic  is known to give people the ride of a lifetime, psychologically speaking, like no other trip, all testify.  Upon returning to earth from planet Ayahuasca, Graham said he saw the light.  His use of cannabis was a problem, his existence had devolved into self absorption with paranoia about non-existent issues.  His mistress was the herb cannabis and not his lovely wife.  He decided that the paranoia had to go, and his mistress Cannabis, as lovely was, she was had to go.


Is that not the greatest "drug abuse" story ever told?  We should all be so lucky.  Substitute in pain killers, booze, cigarettes, or virtually and drug and you would have near 100% dead Elvis, Jackson, Prince, Joplin and so on, with the only exception being Keith Richards.




Plenty of insiders say that every 100m finalist was on Perfromance Enhancing Drugs.



Cycling means to use something for a time and then give it a rest.  In the case of steroids, if they are used too long, natural testosterone shuts down, and the body produces estrogen, in an effort to balance the system.   Extreme abuse results in an extremely unbalanced psychological profile.  Organs can grow or shrink, which results in physical collapse sooner or later.  


However, athletes that cycle, do blood work to see that their bodies vital signs and organ function is not out of whack fare far better, to the point, where it can be argued that moderate steroid use in cycles might actually be beneficial.


The body builds up a tolerance to any herbal, alcohol, drugs, a food.  Small amounts are not an issue.  We're not talking about two glasses of wine in the evening, we're talking about one bottle or more.  Similarly, smoking pot for an hour in the evening is not the issue, smoking many hours every day, is an amount that could cause pot to become toxic.


This is true of vitamins and herbs, where concentrated forms benefit for a while, until the body has too much and resistance and tolerance takes place.  At this point, your herbals are working against you.


While its is trumpeted that marijuana can't hurt you, this idea flies in the face of common sense.

What is apparent is that marijuana is very safe, and it is very uncommon for moderate marijuana smokers to experience significant negative effects.  Nonetheless, if you accept the cycling principle, everyone would benefit more from the medicinal effects of cannabis if they took a holiday from time to time.   

The average cycle time, perhaps in many things, exercise, performance enhancing drugs, is something like 1:3 or 2:7, which translates into three days on one day off, or 5 days on and two days off.  In athletics, ten weeks is normal to buildup overall energy resources.  Then, most coaches found that it is time to move to more intense work, and again this phase lasts for two months or something like that.


10 Medical Marijuana Industry Facts




Or you might be smoking moldy pot, weed with chemical sprays in it.  


  • What are the signs and symptoms?

  • How does pot become toxic?

  • Is it your pot making you sick, or are there chemicals in it?

  • What to do if your pot makes you sick?

  • Should I take a break from pot ?

"Paraquat and other chemical sprays are endorsed, pushed throughout the world by the UN, WHO, DEA, EPA, in a process of classic Orwellian doublespeak, saying they are helping protect people and the environment, while sabotaging human, plant and animal life at all levels."


The Cannabinoid hyperemesis syndrome is characterized by recurrent nausea, vomiting and crampy abdominal pain. These symptoms have been reported to be improved temporarily by taking a hot shower or bath or more fully by stopping the use of cannabis.

The syndrome was described by several doctors about a decade ago. A study of  nearly one hundred cannabinoid hyperemesis syndrome "confirmed earlier findings.   By confirmed, we mean to say that this is but one study, where extraneous variables may not have been thoroughly investigated; such as testing for pesticides, herbicides, aflatoxins, and profiling the cannabis, the amounts of THC, CBD and the terpenes.   In other words, much of earlier and present research is incredibly naive ....



Let's spray this marijuana with Paraquat and see what happens



For example: this peer reviewed paper makes no mention of any of the confounding factors listed above. Cannabinoid hyperemesis syndrome: Clinical diagnosis of an underrecognized manifestation of chronic cannabis abuse.  This lack of basic cannabis acumen - or lack of ability to communicate - renders this paper nearly useless.  Such is the plight of the peer review process today.

The long-term and short-term effects of cannabis use are associated with behavioural effects leading to a wide variety of effects on the body systems and physiologic states.

A Dr. Sontineni and colleagues in 2009 discussed the cannabinoid hyperemesis syndrome to offer guidelines for the clinical diagnosis, such as complications that can lead to acute kidney injury.  

His group reports severe cyclic nausea and vomiting is resolved by stopping the use of cannabis. Symptoms of cannabinoid hyperemesis syndrome was relieved with hot showers or baths.  Others reported abdominal pain and weight loss.

Various mechanisms are proposed to explain the symptoms of cannabinoid hyperemesis syndrome with the most popular being:


  • dose dependent buildup of cannabinoids and related effects of cannabinoid toxicity

  • the functionality of cannabinoid receptors in the brain and particularly in the hypothalamus (which regulates body temperature and the digestive system)




At the end of the day, anyone exhibiting symptoms of the cannabinoid hyperemesis syndrome should discontinue weed and see if symptoms persist.  At the very minimum, change the strain you smoke.




Fake Studies &The Red Flag -  No elementary test data about the weed is provided such as mold, pesticides, heavy metals, CBD and THC and terpenes.  


Cannabis toxicity could well be caused by chemical additives and mold - the symptoms are identical to classical poisoning - if one is experiencing these symptoms, one should discontinue the use of weed.   If a person wishes to resume marijuana use, they should consider using a strain that's been tested - showing that it is pesticide and mold free.  Also strains that are balanced in CBD & THC or contain mostly CBD alone might not cause toxic reactions.   


Treatment is straightforward.

Many traditional medications for nausea and vomiting exist, but if you want pharmaceuticals, . treatment with lorazepam or haloperidol has provides relief for some people. You want to address dehydration due to vomiting by taking electrolyte solutions (Gatorade is the worst).

There are reports of renal failure due to electrolyte deficiency, which can be easily shored up simply by drinking a solution with mostly salt (sodium chloride) plus smaller amounts of potassium, calcium and magnesium, in ratios that are present in normal plasma (blood).


Acute episodes of cannabinoid hyperemesis are reported to last for 24–48 hours and normally resolves with stopping the use of cannabis use, however, improvement can take something like  three months.





laughCannabinoid Hyperemesis Syndrome. I never saw this until about 4 years ago. Now I see it a handful of times per year. Do the other health care professionals of Meddit see it much?

laughYep, saw two cases so far in the last six months, including one ICU admission that had such completely out of whack electrolytes that it took three days for us to stabilize things enough for them to have a coherent conversation to get a history. Turns out it was caused by using one of the synthetic cannabinoids and the patient had been vomiting for over a week with only temporary relief with hot baths.

laughI also saw something similar to this on internal med. Also caused by a synthetic cannabinoid.

laughWould it look like a gall bladder flare up with no verifiable cause? I went in for that and the docs said there were 6 other similar cases at the time...

laughConstant vomiting only relieved by hot bath/shower has been the presentation I've seen.

laughAlso associated with Erythema Ab Igne probably due to constantly using heat to self-treat the nausea.

laughThe problem is that since marijuana is widely known to be an antiemetic for most people these folks will continue to smoke because for a few minutes it does help. For some reason the guy I saw really didn't want to believe that getting nauseated like 5 minutes later and continuing to be nauseated was... because of the ganja. Hard to give it up when you smoke it enough that it makes you sick.

laughI've seen many problems that have come from the synthetic marijuana stuff, but never any from actual pot.

laughThe worst things I've seen that came from marijuana consumption have been auto accident related and a young woman who had smoked what she described as "moldy looking" pot that led to a pretty severe fungal infection in her upper respiratory.

laughFunny, all of mine have been smoking the weed.

laughMy ex-partner has this from the copious daily usage of regular old marijuana. Nothing synthetic.

laughSeen it three times in the last year. Hilarious. Hallmark is hot showers make it better. Guys just say hey man if I can smoke a bowl, it feels okay for a minute. Takes forever to convince them that the weed is the problem.

laughYeah, they really don't want it to be the weed! Can't blame em. I've seen 2 in just 1 month on a GI service.

laugh"Hallmark is hot showers to make it better." God's cruel joke on the hippies

laughI've heard several times that some patients with this outright reject the diagnosis because of their denial that it could be the weed.

laughIt's is often the biggest hurdle to treatment, as the treatment is--gasp--to stop smoking weed.

laughI have seen several cases in the ED. Presents just like gastroparesis except no diabetes. Otherwise healthy, but when pressed, report MJ use. One patient, even had a cholecystectomy even though it had a normal RUQ US, but had an abnormal cholescintigraphy. Symptoms returned after the chole, surprise, finally admits to MJ use.

laughYep. Seen it 3 times in the last 6 months and highly suspected it in another case. Could be because I'm in Washington state. Two of the patients had extensive past workups with cholecystectomy and 'abdominal migraine' diagnosis.

laughMany times. It does indeed present like any number of GI ailments, but the frequent hot showers and chronic usage of chronic set it apart. We see it a few times a month is CA. First documented in 2004 and chronic marijuana usage actually induces gastroparesis IIRC.

laughI have included this into my differential for cyclic vomiting. Anyone who does not suffer from diabetic gastroparesis who presents to my ED with recurrent symptoms get a urine drug screen. I'm surprised to find that a majority of these patients in my practice uses THC routinely. The diagnosis is further suspected when patients admit to relief with hot showers. I tell patients my suspected diagnosis without any judgment, but most are resistant to it. Their usual response is that they use the cannabis to treat the hyperemesis.

laughTheir usual response is that they use the cannabis to treat the hyperemesis.Talk about a perfect storm...

laughPediatrics resident here. Saw it my second week of residency and at least one more time since then but that one is more suspected.

laughI've never seen this before, never heard of it either. and I'm from the Netherlands :')

laughThat would be incredible since I'm a PhD student now :P  Oh and usually cannabis users don't end up in the hospital here.

laughTHC has such a tremendous affect on appetite, I could see how chronic use could lead to something like this.

laughYep. Had the hardest damn time rounding on the kid (male, early 20's) because he was always in the shower.

laughI am friends with many pot smokers and have never seen/heard of this. I have, however, seen people who have "green faced" after smoking too much (acute nausea/vomiting/malaise that resolves in ~30min--happens with new tobacco users too).

laughI think the vast majority of pot smokers are not affected, and the ones that are usually are daily smokers of a large quantity. The thing about taking showers to help then nausea is quite common with it.

laughThey often use up all their hot water, trying to get relief.

laughAny idea on the etiology? Particularly as to why a core temperature change would help (I assume that's what's occurring with long hot baths/showers)?

laughIt's not the temperature that helps, it's the sensation of being in water that almost immediately quells the nausea to a tolerable level. At least in my ex-partner's case.

laughUgh, I can't mix booze and weed because I get this. Starts with vertical nystagmus and ends with puke everywhere.

laughOnly once did I get sick from weed alone.

laughNot a medical pro, but my best friend has it. Had to stop.

laughThis is super late, but hopefully you'll get to see this. I wanted to thank you for sharing this. I saw a patient in the ED yesterday with 2 years of N/V who came in acutely for N/V with some abdominal discomfort yesterday. He had had 10 CTs, EGD/colonoscopies, and even an exploratory laparoscopy in the past 2 years.


laughNo cause of his symptoms could be found. I remembered reading about this on reddit and asked the patient about marijuana use and the hot showers. He admitted to heavy daily marijuana use and he was astounded that I knew that helped him. Well, I ran it by my attending and he had never heard of it, but he surprisingly was interested in reading about it so I gave him a paper. He saw the patient and agreed. I called the guy's PCP because I'm sure he has had a tough time dealing with this the past two years. Anyway, this was really helpful. Thank you.

laughHa! just read it as a result of another post about it. Glad to have helped you make a diagnosis. Keep up the good work.

Another Big Pharma Nightmare

Big Pharma Synthetic Cannabis Kills


laughMy ex-partner has this. He is horribly addicted, it destroyed our relationship.

laughI've seen two case reports of this and each time the use of marijuana was played up while the coincident use of other substances is downplayed in relation to the syndrome. The case report that comes most acutely to mind was in one of the osteopathic publications and they played up the fact that the subject of the case was a chronic recreational user of marijuana, but practically ignored that he has gone on a bender right before the symptoms started. I'm really not sure that it's an actual syndrome, but rather more of a demonization of marijuana.


MMJDOCTORONLINE NOTES - In California, to purchase marijuana legally, it is still required that you have a medical marijuana recommendation from a licensed physician.  In 2018, medical marijuana patients, those with Cannabis ID, will be tax exempt, paying as much as $80 less per ounce, depending on the county your dispensary is in.   


MMJDocuments are accepted at dispensaries, cannabis clubs, cooperatives, delivery services and other points of access.  The process takes only a few minutes, is 100% online, and clients don't pay unless the doctor has approved your application.




U.S. to Resume Using Paraquat on Marijuana

Your government at work?  It's not your government.  It's a techno-monster.  


Like gluten intolerance, it was found that the chemical sprays are bound up in the protein - gluten, and that is what was making people sick.  Similarly, sprays like paraquat, in small amounts, will make you a bit sick, in larger amounts, very ill indeed.  


"Are they trying to eradicate weed or the human being.  And who are they really?"


WASHINGTON, July 13— The director of the Drug Enforcement Administration said today that the Government would use the herbicide paraquat and two others in a stepped-up campaign to eradicate domestically grown marijuana.....

Paraquat and other chemical sprays are endorsed, pushed throughout the world by the UN, WHO, DEA, EPA, in a process of classic Orwellian doublespeak, saying they are helping protect people and the environment, while sabotaging human, plant and animal life at all levels.





What is cannabinoid hyperemesis syndrome (CHS)?

CHS is a nebulous condition where cannabis becomes toxic.  If you smoke a lot of pot and you have classic symptoms; recurrent nausea, vomiting and crampy abdominal pain you might have  CHS . Symptoms may improve temporarily by taking a hot shower or bath.   or more fully by stopping the use of cannabis.

What causes the cannabinoid hyperemesis syndrome?

The Cannabinoid hyperemesis syndrome is generally thought to be caused by heavy, habitual use of cannabis. High THC strains are most often implicated in this disorder.  Foreign organic and chemical toxins in marijuana can also be confused with the THC and / or cannabinoid intolerance.  

"In this condition, the acute (illness) phase of CHS typically lasts for only 24 to 48 hours, but the risk of relapse is high if the patient returns to cannabis use." - Jonathan A. Galli, MD



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