THE MANY ADVANTAGES OF MICRODOSING MARIJUANA
Secrets from the Tour de France are going mainstream - microdosing is a very effective way to medicate.
"Microdosing is a hot topic in orthodox medicine, athletics, pro sports, and now, medical marijuana."
Advantages of Microdosing
cheaper, uses less product
less side effects
better overall results
avoids tolerance, need for larger doses
sustainable, does not compromise the host
Dr. Allan Frankel, an internist in Los Angeles was suffering from a viral infection of the heart. Doctors told him he had 6 months to live. At this time he had only smoked cannabis a few times back in the day. With nothing to lose he acted on the advice of experts, that is, patients that used marijuana to help them overcome cancer and AIDS. They urged the doctor to use if for his heart. Amazingly, a year later a miracle happened, and who really knows what role marijuana really played. With that said, Dr. Frankel says marijuana helped a great deal - at a minimum.
And it surely did not turn him into a pot-head or such.
"I'd been depressed and cannabis stopped the depression, it gave me something to look forward to. My brain was turned on." - Dr. A Frankel
Dr. Frankel would go on to recommend medical marijuana and specializes and recommends low doses or micro-doses of THC and other cannabinoids.
"Cannabinoids are a family of compounds used medically and recreationally. Not all cannabinoids are psychoactive. THC is psychoactive and medicinal, while the second most common compound of cannabis (CBD) is non-psychoactive and is perhaps the most medicinal of all. Other cannabinoids are found in different cannabis types (strains) which provide an array of different medicinal effects."
WHAT IS MICRO-DOSING?
Micro-dosing meas to simply to medicate with small amounts of a substance. A dose may be delivered via vapor (inhaler, Vape, E-cig), sublingually (under the tongue), internally (edible,capsule), transdermally (through the skin).
Micro-singing is gaining popularity in both medical and recreational circles. In principle, if you consider alcohol, cigarettes, coffee and chocolate to be drugs (they do contain compounds listed as drugs in the US pharmacopeia), then if you drink a glass of wine, have a piece of chocolate, one cigarette, or one cup of coffee, then you are microdosing. A couple of glasses of wine is moderate consumption, and eating a couple of large chocolate bars is to ask for trouble at some point.
In medical lingo the administration of doses so low ("subtherapeutic") they are unlikely to produce profound whole-body effects, but the amount is high enough to allow cellular response. Administering a consistently small dose of many types of drugs was found to work slowly and surely to treat conditions and symptoms better than larger doses over the long haul, in many cases.
Many people and their doctors are looking for a quick solution to their problems - in minutes and the concept of minimal effective dose is thrown out the window. Higher doses of drugs results in more profound side effects, more stress on the organism, and a resistance / tolerance to the drug, to the point where it stops working. We opine that the vast majority of patients are taking considerably more medicine that is optimal, by far. In fact, over consumption is chronic and is even encouraged by the medical industry. Shameful.
Microdosing was developed commercially in 2005 by several major pharmaceutical companies in a consortium of clinical trials. The behaviour of five drugs, each with problematic idiosyncrasies. Their results suggested a 70 per cent correspondence between microdosing and full-dose.
Editor's note: In the case of medical marijuana, THC and CBD the evidence suggests that there is a much greater correlation with desirable effects, while side effects are negligible.
The majority of the largest pharmaceutical companies now use microdosing in drug development, and this technique has been provisionally endorsed by both the European Medicines Agency and the US Food and Drug Admin (FDA). Human microdosing now has a foothold in drug discovery-preclinical and clinical trials.
DISCOVERY - MICRODOSING WITH THC - MARIJUANA 2.0
"A quarter of my patients take less than 3 mg of THC a day, which in my opinion is the correct dose. In medicine, with any drug, you look for the minimum-effective-dose. Period."
With microdosing, patients are getting the maximum benefit from the minimum amount, without getting stoned, paranoid or lethargic. Some people are microdosing to subtly regulate their moods, boost their creativity, or enhance their workouts and yoga sessions.
SUSANNAH GROSSMAN - ALPHA WOMAN SAVED BY A BIT OF BUD
Susannah Grossman, a Director of a Communications company out of Denver, takes several small doses through the day.
"It lifts my spirits, relieves the stress and tension that can often build up, and it allows me to approach my work with more keen interest."
Editor's note: This is akin to having a coffee, cigarette or drink, however, the profound difference is that cannabinoids are pretty much non-toxic and possess much lower in addictive properties as compared to the daemon molecules - for those prone to addiction - nicotine, alcohol and sugar (yes sugar). White powder sugar is probably, by far the greatest killer out there, and by a wide margin.
Michael Backes, the author of Cannabis Pharmacy, thinks when prohibition ends, that microdosing could become the most popular way for people to use cannabis. Right now, people that want to microdose faces two hurdles: finding the correct-best minimum dose, and finding the right form of cannabis based medicine.
MARIJUANA - A HIGHLY INDIVIDUAL RESPONSE
The challenge of finding your optimal dose is that it's different for each person. With most drugs, there is a bell curve response. If you give two aspirins each to 100 people, the majority will find it relieves pain, while a few will have negative reactions or some might need 8 pills to get the same relief as the average person. In this respect, Marijuana is very different , there is no majority response.
Medically, the reason for this highly individualized response is that the cannabinoids of marijuana, the THC, CBD, and other compounds found in the plant - support or supplements the natural functioning of the endocannabinoid system, which varies from person to person.
Humans and other mammals have cannabinoid receptors, which are found everywhere in the body; the tissues, organs, and especially the nervous system and brain. The body naturally makes chemicals (endocannabinoids) that fit into these receptors, and together they modulate, regulate and balance the body's systems, everything from digestion to nerve signaling to the immune system response.
Whether by design, coincidence or evolution, the cannabinoids found in the marijuana plant mimic the endocannabinoids made by the body. When the body is unable to make adequate amounts of a particular endocannabinoid, the body may spasm, experience anxiety, the immune system may overreact and so on.
MEET DR. DUSTIN SULAK
Dustin Sulak, a physician and Reiki healer in Maine, has been practicing cannabis medicine since 2009. He says there are always forces, such as microbes and environmental toxins, pushing us away from balance, and other forces, such as the endocannabinoid system, bringing us back.
"Our bodies are already working to prevent dementia, reduce inflammation, and respond to any pathological process, If we can enhance the functioning (or fix the malfunction) of that system, with a little bit of THC (or CBD), then we can benefit." - Dr. Sulak
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Dr. Sulak has developed a protocol for microdosing. "I found that most people have a threshold of cannabis. Under the maximum threshold, they'll experience a gradual increase in health benefits, and above it, they will build a tolerance, where benefits diminish and there are more side effects, like temporary memory loss and clumsiness. I don't establish the perfect optimal dose, but I can teach you how to find it. Here is how I do it.
You abstain from cannabis for two days. Then on day three, consume one mg of THC and one mg of CBD, in tincture or oil form. Before consuming, answer on a scale of one to 10 these three questions: How easy is it to breathe, how comfortable and calm does your body feel and how easy is it for you to smile authentically, to feel content and grateful?"
Write down your scores, and then take the cannabis, wait 45 minutes and answer the questions again. If there's been no change in your scores and there is no effect in mood(obviously). Then increase the dose by one milligram.
Then repeat this process over the next few days increasing the dose by small increments. When you reach a point where you feel a difference after consuming, you've established your minimal effective dose.
Then at this point, add 1 mg each day, until the benefits, the gains stop. At this point you've established your therapeutic range, minimal to effective dose.
Editor's note: Another doctor has found that it takes a couple of weeks for the system to adapt to the introduction of cannabinoids into the system, and this doctor suggests that you adjust the dosage on a three week basis.
HOW TO TREAT MARIJUANA "OVER CONSUMERS"
Dr. Sulak say's that tolerance gets re-set after abstaining for forty eight hours,where you eat and live healthy. Then they follow the stated protocol as new cannabis users, and gradually increase the dose until they feel an effect.
"That's all – that's the magic time when tolerance gets re-set."
Dr. Sulak conducted a survey of forty-eight heavy users that followed the protocol, and found on average that they used less than half the cannabis than before and were getting better results.
"You're saving money, If you're a smoker, you're saving smoke exposure to your lungs, and having less side effects."
Sulak, in contrast to many in the field, believes that THC is the primary health agent in marijuana.
"The idea that THC is recreational and CBD is medical is far from true, THC, milligram for milligram, has a much greater therapeutic effect than CBD. You could treat pain with 3 mg of THC, but it might take 15 to 30 mg of CBD to attain the same relief."
Nonetheless, for overall wellness and disease prevention, he recommends combining THC and CBD, which is consistent with the current mode of thinking of the "medical establishment"..
Previously, few dispensaries cater to microdosing patients and have yet to be educated on this upcoming trend in dosing. A major issues is that in most states it is hard to find cannabis based medicine products that tell you accurately or specifically the quantity of each cannabinoid that is present. However, this will not be the case in California, where marijuana products must be tested and publish the cannabinoid profile and do other testing for mold, pesticides and in some cases terpenes (yet other medicinal ingredients of cannabis).
For example, Hemp Oil from Charlotte's Web is the largest selling CBD oil in the country. It doesn't say on its labels how many mg of CBD is in dropper pull. A director of hemp oil marketing says they don't list the amount to comply with FDA regulations, but they can teach customers to measure the quantity in mg of CBD. This response is friendly enough, but they could easily note the mg per spoon full, or dropper draw, or per milliliter, and in the very near future, they will be required to, by law, most probably in most every state, so goes our prediction.
"You're pretty much on your own, to use trial and error to find what your sweet spot between no detectable effect and stoned." - Susannah Grossman, Director Verdant Communications,
As a student in upstate New York, , Susannah smoked weed regularly, but after taking a job in Manhattan, she stopped because the workplace wasn't an environment where you could be doing such things that were "alternate'. You know, where getting totally drunk after hours is OK and smoking one joint is not...
After moving to her new job in Boston, she worked 75 hours a week and had to take anti-depressants to cope. Then she suffered a seizure directly caused by the anti-depressants and had to stop them cold turkey. Then she rediscovered weed, after reading about how cannabis could help with depression, and incorporated small amounts in her daily regime in a healthy and therapeutic way. The one thing she feared was that she would feel good, but produce less, which is the stereotype of the useless pothead. It did not work out that way, in the same way that drinking one glass of wine will not cause you to jump into the swimming pool naked.
"I had a major fear that I wouldn't be able to write or work, I'd slack off and produce less. But it's been just the opposite. Microdosing has helped me focus and accomplish more."
Grossman then moved to Colorado, where coincidentally she found that with recreational use was legal. (Grossman would surely have qualified for a medical marijuana card.)
In Colorado, you have the luxury of trying an infinite variety of strains, until you find what rings your bell. This a luxury that is not afforded in a in a non-legal state. Wherever she went, she would buy a few grams of new strains,and test them, and then tried different combinations and doses. It took her quite a while to find what works best.
"I'm currently taking a tincture that's 5 mg of both THC and CBD. Then I'll take a puff of a certain strain three or four times a day, if I'm feeling at the end of my runway, or if I'm about to go into a meeting where I need a fresh perspective."
When asked if she's concerned about an addict, she answered no. She takes breaks of several weeks at a time. She keeps a diary and if she notices her consumption rising, then she cuts back or goes on a holiday.
At the end of the day, she hasn't had a seizure since moving to Colorado and she believes it is the CBD that especially prevents this. But then again, she has found that the THC in Sativa strains are particularly enjoyable and it gives me a sense of playfulness.... while happily reports, she's getting a ton of work done the whole while.
MICRODOSING IN SPORTS
Micro-dosing is the new trend in sports doping Forget about injections of sophisticated, powerful steroids, growth hormones and whatnot, when it comes to doping these days, the new trend is micro-dosing.
“Smaller amounts are being taken in the hope that they will be undetectable,” David Howman, director general of the World Anti-Doping Agency (WADA).
MEET MR. VICTOR CONTE
Victor Conte, the man behind the BALCO scandal that jailed former star sprinter Marion Jones and directed Barry Bonds sports "medical" program, agrees.
“I don’t believe they’re using designer steroids these days. I believe they’re using fast-acting testosterone, You can micro-dose, you can use fast-acting creams and gels and patches,” - Victor Conte
“What you’re doing is taking a small amount to give you a little bit extra for the event, and then hopefully it will go through your body so that by the time you finish the event, it won’t come out in your urine or your blood. That’s what they hope,” - Drug Tester
While sportsmen are using microdosing to get the performance enhancing benefits, they are passing the drug tests, so you know that the microdosing process is effective, aveit illegal in the case of non-prescribed performance enhancing drugs. It is a great pity that these advances in sports medicine seldom, if ever, are used in common practice by general practitioners or even specialists. In a nutshell, the medical profession is verging on dysfunctionality. Terrible.
MICRODOSING - BOOST BLOOD - GO FASTER AND LONGER
"If you’re training at altitude you can do 3-400 units of EPO every night at 10pm intravenously and be fine by the morning. You’re only required to answer the door to the testers during your one-hour window, so just make it 9am and you’ll be fine. That’s plenty of time. Over two weeks you’ll raise your HCT [haematocrit - the percentage of oxygen-carrying red blood cells -ed.] by 4-5 points, but if you’re training hard your blood will be diluted and it won’t show on the test for the biological passport, and that’s conservative.”
“You’re fine with 800-1000 units with that amount of clearance time,” he added. “But then your HCT will rise faster so there’ a very small risk with the ABP. Human growth hormone? You can do as much as you want with an hour of clearance time. That alone will raise your HCT by 3-4 points over three weeks and double testosterone production. Once you’ve raised your HCT 4-6 points you’ve got two months of benefit – decreasing gradually over the second month. For the guy who is around 70kg a 6-8 point increase, which is very easy to manage, you’ve got 20-30 extra watts.”
MMJDOCTORONLINE Notes: To purchase marijuana of any kind in California, you must have a medical recommendation from a Medical Doctor. Fortunately, accessing a medical doctor is allowed via the internet in a process called Telemedicine. Just fill out a form - in a few minutes, and a medical doctor evaluates your stated conditions and symptoms from his tablet from a remote, comfortable location.
Patients usually receive their approval for a 420 evaluation, Cannabis ID card, or grower's permit on the same day of application. Please note that patients are not asked to pay unless they are approved. MMJDOCTORONLINE documents are used at dispensaries, delivery services and other legal points of access for medical marijuana (cooperatives, cannabis clubs, etc.). California MMJ ID is accepted at many dispensaries in Nevada too, which reduces the cost of purchase by as much as 35% as a tax exempt patient.
The solution comes in the form of microdosing, which is more than just the latest buzzword in the cannabis industry. Microdosing is all about using smaller amounts of marijuana in order to enjoy its medicinal properties without getting stoned AF.
This mode of cannabis intake has several benefits:
Microdosing is not only effective, but it’s also a practical way for medical marijuana patients to save money without running the risk of indulging unnecessarily.
Microdosing is the ideal way to administer medical marijuana for non-users or patients who are strictly using the plant for its medicinal value.
Microdosing controls the unwanted side effects of taking too much pot, so you can benefit medicinally. By microdosing you are greatly reducing your risk of paranoia, getting the munchies, and other side effects that certain strains give especially when you take it in large doses.
In the winter of 1999, Dr. Allan Frankel, a renowned internist in Los Angeles, suffered a viral infection of the heart. Doctors told him he had six months to live. He'd rarely tried marijuana, but several of his cancer and AIDS patients urged him to use it for his heart. A year later, his heart was normal. Frankel, now 66, says he can't be certain that cannabis healed him – but it certainly helped. "I'd been depressed and cannabis stopped the depression," he says. "It gave me something to look forward to. My brain was turned on."
There are those cannabis connoisseurs who enjoy getting super stoned at the end of a long day at the office, while others are now embracing an emerging trend called microdosing, a procedure that allows the user to moderate their mind by taking small doses throughout the day.
The concept of microdosing is simple: instead of consuming enough THC to join the land of catatonia, the user leans on somewhere between 3 to 10 milligrams to feel some effect without entering into a realm of laughing fits, paranoia and ravenous hunger. It is increasingly popular practice that Rolling Stone calls “Marijuana 2.0,” an idea that less is actually more when it comes to using cannabis for its therapeutic and creativity-inducing benefits.
Cannabis differs from other “drugs” - like alcohol, sleeping tablets or painkillers - in that you do not need to perpetually increase the dosage to get the same effect. From personal experience, I’ve found that it actually seems to be the inverse. Over the years, I am consuming less in order to get as high as I need. The result is my cannabis supply lasts a very long time.
Editor: Is there peer pressure to macrodose? No harm done, there is less consumption, less cost, less chance of overdoing a good thing...and maybe the dose is more beneficial. Probably.
Maybe it has to do with the way that I’m smoking nowadays. When I started to consume cannabis, it was really a social activity. Us students back in the 1990s, friends and I would save up our coins and buy our marijuana (which was usually hashish form - in North East of England). We would stupidly consume as much as we could in as short of a duration as possible. Little did we know that we were actually wasting the majority of the herb we were consuming.
Editor note: Vapes are about 40% more efficient as compared to smoking a joint, in addition, over consumption goes above the sweet recreational spot, making the above method consumption completely wrong on every level.
In an era when cannabis is becoming legal from coast to coast, giant joints and big bong rips are out, while Vapes, E-cigs and microdosing are in.
In layman's terms "microdosing" typically refers to the practice of ingesting small amounts of heavy psychedelics, like LSD and psilocybin mushrooms, as opposed to taking large debilitating quantities common in recreational use. There are a host of reasons pot users should try it out with their drug of choice. Can it change the way you get high? There is a way to find out... try ...
The creator of LSD, Dr. Albert Hofmann, believed that ingesting tiny amounts of the drug could have therapeutic value, and so-called “microdoses” have since been proposed as a substitute for everything from Adderall to marriage counseling. Now, as more states legalize marijuana, the trend that began with hallucinogens has grown to include microdoses of THC, the main psychoactive ingredient in weed.....